Plant Transcription Factor Database
Previous version: v3.0
Raphanus raphanistrum
BES1 Family
Species TF ID Description
RrC1333_p5BES1 family protein
RrC1522_p5BES1 family protein
RrC152_p8BES1 family protein
RrC20339_p1BES1 family protein
RrC2092_p1BES1 family protein
RrC2149_p3BES1 family protein
RrC2280_p1BES1 family protein
RrC2797_p3BES1 family protein
RrC3927_p2BES1 family protein
RrC4885_p3BES1 family protein
RrC6013_p2BES1 family protein
RrC859_p1BES1 family protein
RrC947_p3BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330